•
Mar 31

Argenx Q1 2025 Earnings Report

argenx reported strong first quarter results with nearly doubled product sales and a return to profitability.

Key Takeaways

argenx delivered robust revenue growth in Q1 2025 with product net sales reaching $790 million and reported a net profit of $169 million, reversing a loss from the previous year. Strong momentum in VYVGART launches and expansion supported commercial performance.

Product net sales grew to $790 million, a 99% increase from Q1 2024.

Reported net income reached $169 million, up from a loss of $62 million in Q1 2024.

Diluted EPS turned positive at $2.58 compared to a loss of $1.04 in Q1 2024.

Global launch of VYVGART-SC PFS and continued pipeline progress supported growth trajectory.

Total Revenue
$807M
Previous year: $398M
+102.7%
EPS
$2.58
Previous year: -$1.04
-348.1%
YoY Product Sales Growth
99%
Diluted EPS
$2.58
Previous year: -$1.04
-348.1%
Gross Profit
$727M

Argenx

Argenx

Argenx Revenue by Segment

Forward Guidance

argenx maintains full-year guidance for combined R&D and SG&A expenses and expects continued momentum from pipeline and product expansion.

Positive Outlook

  • VYVGART SC PFS launched in US and Germany, broadening administration options.
  • CHMP positive opinion supports further CIDP expansion in Europe.
  • Continued clinical momentum across multiple Phase 2 and Phase 3 programs.
  • Robust sales growth across all VYVGART indications and geographies.
  • Financial guidance for $2.5B in operating expenses reaffirmed.

Challenges Ahead

  • Significant R&D and SG&A costs ($668M in Q1) weigh on margins.
  • Dependence on success of ongoing and upcoming clinical readouts.
  • No revenue breakdown by geography limits regional visibility.
  • Profitability improvement partially driven by exchange gains.
  • Continued investment in early-stage pipeline impacts short-term earnings.