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Mar 31

Absci Q1 2025 Earnings Report

Absci reported a wider net loss and higher R&D expenses while launching its first clinical trial.

Key Takeaways

Absci reported Q1 2025 revenue of $1.2M with a net loss of $26.3M, driven by increased R&D investments. The company began dosing in its ABS-101 clinical trial and strengthened its pipeline momentum.

Revenue rose to $1.2M, up from $0.9M in Q1 2024

Net loss widened to $26.3M driven by increased R&D expenses

Cash and short-term investments reached $134M, supporting runway into 2027

Initiated first-in-human study for lead antibody program ABS-101

Total Revenue
$1.18M
Previous year: $898K
+31.3%
EPS
-$0.21
Previous year: -$0.22
-4.5%
Gross Use of Cash
$26.3M
Cash and Equivalents
$47M
Previous year: $58.8M
-20.1%
Total Assets
$232M
Previous year: $275M
-15.4%

Absci

Absci

Absci Revenue by Segment

Forward Guidance

Absci plans to advance multiple programs through preclinical and clinical development while maintaining financial flexibility with its current cash runway into 2027.

Positive Outlook

  • Cash position supports operations into H1 2027
  • Interim data readout for ABS-101 expected in H2 2025
  • ABS-201 Phase 1 initiation targeted for early 2026
  • NHP data supports clinical development of ABS-201
  • Strong pipeline including internal and partnered programs

Challenges Ahead

  • Continued net losses expected due to R&D investments
  • No commercial products yet generating recurring revenue
  • High reliance on future partnerships to sustain growth
  • Limited revenue diversification at this stage
  • Stock-based compensation contributing to rising costs