Dec 31, 2021

Adaptimmune Q4 2021 Earnings Report

Adaptimmune reported financial results for the fourth quarter and full year ended December 31, 2021, and provided a business update.

Key Takeaways

Adaptimmune reported fourth quarter revenue of $1.4 million and is focused on filing its first BLA, building its MAGE-A4 franchise, scaling up its manufacturing capabilities, and making progress with its allogeneic platform in 2022. The company's cash, cash equivalents and marketable securities are expected to fund operations into early 2024.

SPEARHEAD-1 met its primary endpoint - planning for afami-cel BLA submission in Q4 2022 for people with synovial sarcoma

Moving to late-phase development with ADP-A2M4CD8: SURPASS-2 initiated in esophageal and EGJ cancers; initiating SURPASS-3 in ovarian cancer in 2022

Allogeneic platform on-track for planned IND submission in 2023 for first product targeting MAGE-A4

Started our strategic collaboration for allogeneic T-cell therapies with Genentech - $150 million upfront payment received

Total Revenue
$1.42M
Previous year: $1.5M
-5.7%
EPS
-$0.25
Previous year: -$0.24
+4.2%
Gross Profit
-$28.1M
Previous year: -$24.3M
+15.7%
Cash and Equivalents
$150M
Previous year: $56.9M
+163.6%
Free Cash Flow
$130M
Previous year: -$30.4M
-527.6%
Total Assets
$470M
Previous year: $451M
+4.1%

Adaptimmune

Adaptimmune

Forward Guidance

The Company believes that its existing cash, cash equivalents and marketable securities, together with the upfront and additional payments under the Strategic Collaboration and License Agreement with Genentech, will fund the Company’s current operations into early 2024.