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Jun 30, 2024

Adverum Q2 2024 Earnings Report

Adverum reported financial results for the second quarter of 2024 and provided Ixo-vec program and corporate highlights.

Key Takeaways

Adverum Biotechnologies reported their Q2 2024 financial results, highlighting the selection of the 6E10 dose of Ixo-vec for Phase 3 pivotal trials and the presentation of the LUNA 26-week interim analysis. They also announced $173.8 million in cash, cash equivalents and short-term investments expected to fund operations into late 2025.

6E10 dose of Ixo-vec was selected for Phase 3 pivotal trials.

LUNA 26-week interim analysis was presented at ASRS 2024, demonstrating a potential best-in-class product profile of Ixo-vec.

LUNA 9-month landmark analysis and pivotal trial design update are anticipated in 4Q 2024.

Cash, cash equivalents and short-term investments of $173.8 million are expected to fund operations into late 2025.

Total Revenue
$0
0
EPS
-$0.89
Previous year: -$3.1
-71.3%
Gross Profit
-$956K
Cash and Equivalents
$174M
Previous year: $142M
+22.8%
Free Cash Flow
-$19.9M
Previous year: -$23.3M
-14.7%
Total Assets
$254M
Previous year: $241M
+5.1%

Adverum

Adverum

Forward Guidance

Adverum anticipates several milestones in the near future, including regulatory interactions, clinical data releases, and trial design updates.

Positive Outlook

  • Continued FDA and EMA formal and informal regulatory interactions are expected.
  • Clinical data from the landmark LUNA 9-month analysis is anticipated in 4Q 2024.
  • A Phase 3 pivotal trial design update is expected in 4Q 2024.
  • Clinical data from the landmark LUNA 52-week analysis is expected in 1Q 2025.
  • Planned initiation of Phase 3 trial in H1 2025.

Challenges Ahead

  • Adverum’s novel technology makes it difficult to predict the timing of commencement and completion of clinical trials.
  • Regulatory uncertainties could impact the development timeline.
  • Enrollment uncertainties may affect the progress of clinical trials.
  • The results of early clinical trials may not be predictive of future clinical trials and results.
  • There is a potential for future complications or side effects in connection with the use of Ixo-vec.