Dec 31, 2021

Altimmune Q4 2021 Earnings Report

Altimmune reported financial results for Q4 2021 and provided a corporate update.

Key Takeaways

Altimmune reported a revenue of $3.3 million for the three months ended December 31, 2021, compared to $2.3 million in the same period in 2020. The net loss for the three months ended December 31, 2021 was $23.9 million, or $0.57 net loss per share, compared to $10.6 million in the same period in 2020, or $0.29 net loss per share. The company had cash, cash equivalents, short-term investments and restricted cash totaling $190.3 million at December 31, 2021.

Data readouts from multiple clinical trials expected during the next 6 to 12 months

Strong cash position of $190.3 million as of December 31, 2021

Initiation of the Phase 2 MOMENTUM trial of pemvidutide in obesity expected in the first quarter of 2022

Topline data from the extension trial expected in Q4 2022.

Total Revenue
$3.28M
Previous year: $2.31M
+41.7%
EPS
-$0.57
Previous year: -$0.17
+235.3%
Gross Profit
-$17.8M
Previous year: -$12.7M
+40.0%
Cash and Equivalents
$190M
Previous year: $116M
+64.2%
Free Cash Flow
-$22.1M
Previous year: -$13.5M
+63.6%
Total Assets
$219M
Previous year: $245M
-10.7%

Altimmune

Altimmune

Forward Guidance

Altimmune anticipates value-creating data readouts from multiple clinical trials in the next 12 months and expects to read out their HepTcell trial in the first half of 2023.

Positive Outlook

  • Phase 1b nonalcoholic fatty liver disease (NAFLD) trial data readout expected in Q3 2022
  • Interim analysis planned to assess changes in body weight after 24 weeks of treatment, with an expected readout in Q4 2022
  • Topline data from the extension trial expected in Q4 2022
  • Results of a drug-drug interaction trial of pemvidutide expected in the first half of 2022
  • Study readout for Phase 2 clinical trial in chronic hepatitis B subjects, with study readout expected H1 2023

Challenges Ahead

  • Potential impacts due to crises, including conflicts and wars (like the ongoing conflict in Ukraine) and pandemics (like the COVID-19 pandemic), such as delays in regulatory review, manufacturing and supply chain interruptions, access to clinical sites, enrollment, adverse effects on healthcare systems and disruption of the global economy
  • The reliability of the results of studies relating to human safety and possible adverse effects resulting from the administration of the Company’s product candidates
  • The Company’s ability to manufacture clinical trial materials on the timelines anticipated
  • The success of future product advancements, including the success of future clinical trials
  • Timing of key milestones for clinical assets