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Mar 31, 2022

Amylyx Q1 2022 Earnings Report

Amylyx reported financial results for the quarter ended March 31, 2022.

Key Takeaways

Amylyx Pharmaceuticals reported a net loss of $47.8 million for the first quarter of 2022. The company is focused on commercial launch readiness to support AMX0035 for ALS treatment and engaging with regulators for potential approvals.

Regulatory applications for AMX0035 are under review in the U.S., Canada, and Europe.

New analyses from the CENTAUR trial demonstrated a significant survival benefit of AMX0035.

Safety and tolerability data from CENTAUR and PEGASUS trials were presented at the 2022 AAN Annual Meeting.

An Expanded Access Program (EAP) for AMX0035 was launched in the U.S. for eligible people living with ALS.

EPS
-$0.93
Previous year: -$0.316
+194.3%
R&D Expenses
$21.5M
Previous year: $6.86M
+212.7%
G&A Expenses
$26.4M
Previous year: $6M
+338.9%
Cash and Equivalents
$255M
Free Cash Flow
-$41M
Total Assets
$274M

Amylyx

Amylyx

Forward Guidance

The company is focused on advancing AMX0035 through regulatory processes and preparing for potential commercial launch.

Positive Outlook

  • Potential regulatory approval of AMX0035 in the U.S., Canada, and Europe.
  • Ongoing Phase 3 PHOENIX clinical trial evaluating AMX0035.
  • Commitment to bringing new and effective treatments to the ALS community.
  • Positive safety and efficacy data supporting AMX0035.
  • Expanded Access Program providing access to AMX0035 for eligible patients.

Challenges Ahead

  • Uncertainty regarding the timing of FDA review and potential approval of AMX0035.
  • Dependence on the success of AMX0035.
  • Risks associated with clinical trials and regulatory processes.
  • Potential impact of the COVID-19 pandemic on operations.
  • Competition from other companies developing treatments for ALS.