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Dec 31, 2022

Annexon Q4 2022 Earnings Report

Annexon reported fourth quarter and year-end 2022 financial results and reiterated anticipated milestones.

Key Takeaways

Annexon reported a net loss of $34.4 million for the quarter ended December 31, 2022, and cash and cash equivalents and short-term investments were $242.7 million as of December 31, 2022.

Initiated dosing in Phase 1 Multiple-Ascending Dose (MAD) Trial of ANX1502.

Completed expanded enrollment in the ongoing pivotal Phase 3 trial of ANX005 in patients with Guillain-Barré syndrome (GBS) in 2023 with pivotal data anticipated in the first half of 2024.

Completed the ongoing SAD trial of ANX1502 and identify the maximum tolerated dose; execute the ongoing MAD trial in healthy volunteers; and initiate a proof-of-concept study in patients with cold agglutinin disease (CAD) in 2023.

Completed the ongoing Phase 2 trial of ANX007 in patients with geographic atrophy (GA) and report initial data in mid-2023 followed by additional data by the end of 2023 after the conclusion of the six-month off-treatment period.

EPS
-$0.48
Previous year: -$0.97
-50.5%
Research and Development Expenses
$28.5M
General and Admin Expenses
$8.16M
Cash and Equivalents
$140M
Previous year: $74.8M
+87.1%
Free Cash Flow
-$27.4M
Previous year: -$29.2M
-6.0%
Total Assets
$285M
Previous year: $287M
-0.7%

Annexon

Annexon

Forward Guidance

Annexon expects its cash, cash equivalents and marketable securities as of December 31, 2022, to be sufficient to fund the company’s current operating plan into 2025.