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Dec 31, 2024

Astria Q4 2024 Earnings Report

Astria reported an increased net loss in Q4 2024, driven by higher R&D and G&A expenses as it advanced its clinical programs.

Key Takeaways

Astria Therapeutics reported a net loss of $25.6 million for Q4 2024 as the company increased its research and development spending for its lead programs. Despite this, the company maintains a strong cash position, which is expected to support operations into mid-2027. The Phase 3 trial for navenibart is underway, and Astria expects key data readouts in 2025.

Net loss for Q4 2024 was $25.6 million, improving from a $31.4 million loss in Q4 2023.

R&D expenses rose to $20.2 million in Q4 2024, up from $11.7 million in Q4 2023.

G&A expenses increased to $9.4 million, compared to $7.3 million in Q4 2023.

Cash and short-term investments stood at $328.1 million, expected to fund operations into mid-2027.

Total Revenue
$0
0
EPS
-$0.44
Previous year: -$0.86
-48.8%
Net Cash Used in Operating Activities
-$17.4M
Previous year: -$30.2M
-42.4%
R&D Expenses
$20.2M
Previous year: $11.7M
+72.6%
G&A Expenses
$9.4M
Previous year: $7.3M
+28.8%
Cash and Equivalents
$59.8M
Previous year: $247M
-75.8%
Total Assets
$342M
Previous year: $255M
+34.4%

Astria

Astria

Forward Guidance

Astria expects continued investment in its clinical programs, with cash reserves supporting operations into mid-2027. Key data readouts for navenibart and STAR-0310 are expected in 2025.

Positive Outlook

  • Strong cash position of $328.1 million to fund operations into mid-2027.
  • Phase 3 trial for navenibart progressing as planned.
  • Initial safety and efficacy data for ALPHA-SOLAR expected mid-2025.
  • STAR-0310 Phase 1a trial ongoing, with results anticipated in Q3 2025.
  • Market research indicates strong physician interest in navenibart.

Challenges Ahead

  • Increased R&D expenses impacting short-term financials.
  • G&A costs continue to rise due to company expansion.
  • Net loss remains significant despite lower cash burn in Q4.
  • Market competition in the hereditary angioedema space remains high.
  • Regulatory uncertainties could impact future product approvals.