•
Dec 31, 2023

Aura Biosciences Q4 2023 Earnings Report

Reported financial results for the fourth quarter and year ended December 31, 2023, and provided recent business highlights.

Key Takeaways

Aura Biosciences reported increased research and development expenses and general and administrative expenses for the fourth quarter of 2023, leading to a higher net loss compared to the same period in 2022. The company's cash and cash equivalents totaled $226.2 million as of December 31, 2023, sufficient to fund operations into the second half of 2026.

Global Phase 3 CoMpass trial actively enrolling patients for small choroidal melanoma and indeterminate lesions.

Received SPA agreement from FDA for the CoMpass trial design.

Phase 2 data showed positive tumor control and visual acuity preservation rates with bel-sar.

Phase 1 trial of bel-sar in bladder cancer is ongoing, with data expected in mid-2024.

Total Revenue
$2.06M
EPS
-$0.5
Previous year: -$0.52
-3.8%
R&D Expenses
$20.3M
G&A Expenses
$4.5M
Gross Profit
$1.73M
Cash and Equivalents
$41.1M
Previous year: $122M
-66.2%
Free Cash Flow
-$17.7M
Previous year: -$18.4M
-3.6%
Total Assets
$255M
Previous year: $224M
+13.9%

Aura Biosciences

Aura Biosciences

Forward Guidance

Aura Biosciences is focused on advancing bel-sar through clinical trials for choroidal melanoma and bladder cancer, with key milestones expected in the near term.

Positive Outlook

  • Advancing bel-sar in Phase 3 trial for choroidal melanoma.
  • Positive Phase 2 data supports bel-sar's efficacy in ocular oncology.
  • Expanding bel-sar into bladder cancer with ongoing Phase 1 trial.
  • Strong cash position to fund operations into the second half of 2026.
  • SPA agreement with FDA provides regulatory clarity for Phase 3 trial.

Challenges Ahead

  • Clinical trials are subject to uncertainties and may not yield desired results.
  • Regulatory approvals are not guaranteed.
  • Interim data may not be predictive of final results.
  • Competition from existing and emerging therapies.
  • Potential delays or setbacks in clinical development programs.