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Mar 31, 2024

Axsome Q1 2024 Earnings Report

Axsome reported strong financial performance driven by on-market products and advanced its neuroscience pipeline in the first quarter of 2024.

Key Takeaways

Axsome Therapeutics reported a total net product revenue of $75.0 million for Q1 2024, representing a 160% year-over-year growth. The company progressed its clinical trials, including positive Phase 3 results for AXS-12 in narcolepsy, and is preparing for NDA resubmissions for AXS-07 and AXS-14.

Total net product revenue reached $75.0 million, a 160% increase year-over-year.

Auvelity net product sales were $53.4 million, reflecting a 240% year-over-year growth.

Sunosi net product revenue amounted to $21.6 million, a 64% increase year-over-year.

Positive Phase 3 trial results were announced for AXS-12 in narcolepsy.

Total Revenue
$75M
Previous year: $94.6M
-20.7%
EPS
-$1
Previous year: -$0.26
+284.6%
R&D Expenses
$36.8M
Previous year: $17.8M
+106.9%
SG&A Expenses
$99M
Previous year: $74.2M
+33.4%
Shares Outstanding
47.46M
Previous year: 43.55M
+9.0%
Gross Profit
$66.9M
Previous year: $87M
-23.2%
Cash and Equivalents
$331M
Previous year: $247M
+34.5%
Free Cash Flow
-$53.6M
Previous year: -$5.89M
+809.1%
Total Assets
$546M
Previous year: $389M
+40.2%

Axsome

Axsome

Forward Guidance

Axsome believes that its current cash is sufficient to fund anticipated operations into cash flow positivity, based on the current operating plan.

Positive Outlook

  • NDA resubmission for AXS-07 in migraine targeted for Q2 2024
  • NDA submission for AXS-14 in fibromyalgia targeted for Q2 2024
  • Phase 3 ADVANCE-2 trial of AXS-05 for Alzheimer’s disease agitation topline results expected in 2H 2024
  • Phase 3 open-label safety extension trial of AXS-12 in narcolepsy topline results expected in 2H 2024
  • Phase 3 FOCUS trial of solriamfetol in ADHD in adults topline results expected in 2H 2024

Challenges Ahead

  • Phase 3 PARADIGM trial of solriamfetol in major depressive disorder topline results expected in 2025
  • Phase 3 ENGAGE trial of solriamfetol in binge eating disorder topline results expected in 2025
  • Phase 3 EMERGE trial of AXS-07 in migraine with inadequate response to oral CGRP inhibitors topline results expected in 2H 2024
  • Phase 3 trial of solriamfetol in shift work disorder initiation expected in Q2 2024
  • Phase 3 ACCORD-2 trial of AXS-05 for Alzheimer's disease agitation enrollment completion expected mid-year 2024