Sep 30, 2022

Biomea Fusion Q3 2022 Earnings Report

Reported third quarter 2022 financial results and business highlights.

Key Takeaways

Biomea Fusion reported a net loss of $22.9 million for the third quarter of 2022, with a cash position of $133.8 million. The company continued to advance its pipeline, including BMF-219 and BMF-500, and expects to provide an update on its third development candidate in the first half of 2023.

Continued to establish Biomea Fusion as the next-generation leader in covalent medicines.

Expanded clinical development footprint of BMF-219 in multiple liquid and solid tumor indications, including first in class potential in KRAS-mutated solid tumors.

Continued to advance company’s second product candidate, BMF-500, a highly selective and potent covalent third generation FLT3 inhibitor, toward the clinic.

Cash position of $133.8 million at the end of the third quarter of 2022.

EPS
-$0.78
Previous year: -$0.43
+81.4%
Gross Profit
-$344K
Cash and Equivalents
$134M
Previous year: $192M
-30.3%
Free Cash Flow
-$16.7M
Previous year: -$11M
+51.8%
Total Assets
$145M
Previous year: $199M
-27.3%

Biomea Fusion

Biomea Fusion

Forward Guidance

Biomea Fusion plans to submit IND for BMF-219 in type 2 diabetes patients before the end of 2022 and present clinical updates for AML/ALL and type 2 diabetes patients in the first half of 2023. They also plan to submit IND for BMF-500 in patients with FLT3 mutations in the first half of 2023 and provide an update on their third development candidate in the first half of 2023.

Positive Outlook

  • Submit IND for BMF-219 in type 2 diabetes patients before the end of 2022
  • Present clinical update of AML/ALL patients (including those with MLL rearrangement and NPM1 mutation), dosed in COVALENT-101 study in the first half of 2023
  • Present clinical update on type 2 diabetes patients in the first half of 2023
  • Submit IND for BMF-500 in patients with FLT3 mutations in the first half of 2023
  • Present clinical update of the healthy volunteer section of our Phase I/II type 2 diabetes COVALENT-111 study of BMF-219 at a scientific meeting in 2023