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Jun 30, 2021

Caribou Biosciences Q2 2021 Earnings Report

Reported business highlights and financial results for the second quarter of 2021.

Key Takeaways

Caribou Biosciences reported a net loss of $14.3 million for the second quarter of 2021. The company completed an upsized IPO raising $349.6 million in gross proceeds and dosed the first patient in Phase 1 clinical trial of CB-010.

Dosed the first patient in Phase 1 clinical trial of CB-010.

Completed upsized IPO raising $349.6 million in gross proceeds.

Expanded Caribou’s board of directors with appointment of Nancy Whiting, Pharm.D.

Published data demonstrating the significantly improved specificity of Caribou’s proprietary CRISPR hybrid RNA-DNA (chRDNA) guide technology compared to all-RNA guides.

Total Revenue
$1.48M
Previous year: $8.48M
-82.6%
EPS
-$1.39
Previous year: -$0.0677
+1953.5%
R&D Expenses
$12.3M
Previous year: $7.58M
+62.6%
G&A Expenses
$5.11M
Previous year: $3.15M
+62.2%
Cash and Equivalents
$130M
Free Cash Flow
-$17M
Total Assets
$158M

Caribou Biosciences

Caribou Biosciences

Caribou Biosciences Revenue by Segment

Forward Guidance

Caribou expects initial data from the ongoing ANTLER Phase 1 trial in patients with relapsed or refractory B-NHL in 2022. Caribou expects to file an Investigational New Drug (IND) application for its CB-011 program in 2022. Caribou expects to file an IND application for its CB-012 program in 2023. Caribou expects to announce target selection for its CB-020 program in 2022.

Positive Outlook

  • Initial data from the ongoing ANTLER Phase 1 trial in patients with relapsed or refractory B-NHL is expected in 2022.
  • An Investigational New Drug (IND) application for its CB-011 program is expected to be filed in 2022.
  • An IND application for its CB-012 program is expected to be filed in 2023.
  • Target selection for its CB-020 program is expected to be announced in 2022.
  • CB-010 is an allogeneic anti-CD19 CAR-T cell therapy derived from healthy donor T cells engineered using Cas9 chRDNA technology.

Challenges Ahead

  • Risks inherent in drug development
  • Risks associated with the initiation, cost, timing, progress and results of current and future research and development programs
  • Risks associated with preclinical studies
  • Risks associated with clinical trials
  • Uncertainties in forward-looking statements