4D Molecular Therapeutics reported full year 2021 financial results, highlighting clinical data updates on multiple programs, advancement of additional programs into clinical development, and initiation of GMP manufacturing facility expansion. The company's cash, cash equivalents, and investments of $315 million are expected to fund operations into the second half of 2024.
Provided clinical data updates on three programs, including first clinical data on 4D-310 for Fabry disease and 4D-125 and 4D-110 for inherited retinal dystrophies.
Advanced two additional programs into clinical development: R100 vector-based 4D-150 for wet AMD, and A101 vector-based 4D-710 for cystic fibrosis.
Initiated expansion of GMP manufacturing facilities for potential commercial-scale clinical manufacturing capabilities.
Cash, cash equivalents and investments expected to fund operations into the second half of 2024.
4DMT anticipates several milestones and objectives for 2022, including first patient dosing in the 4D-710 Phase 1/2 clinical trial for cystic fibrosis expected in the first half of 2022 and continuation of enrollment and follow-up in multiple Phase 1/2 clinical trials.