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Sep 30, 2024

Insmed Q3 2024 Earnings Report

Insmed's Q3 2024 earnings were reported, featuring revenue growth and progress in clinical and regulatory milestones.

Key Takeaways

Insmed reported Q3 2024 financial results, with total revenue reaching $93.4 million, an 18% increase year-over-year. The company is on track to file an NDA for brensocatib in Q4 2024 and anticipates a potential U.S. launch in mid-2025. Insmed ended the quarter with approximately $1.5 billion in cash, cash equivalents, and marketable securities.

Total revenue for Q3 2024 was $93.4 million, reflecting an 18% increase year-over-year.

ARIKAYCE global revenue grew by 18% compared to Q3 2023, with double-digit growth in the U.S., Japan, and Europe.

The NDA submission for brensocatib in bronchiectasis is on track for Q4 2024, with a potential U.S. launch expected in mid-2025.

Insmed ended the third quarter with approximately $1.5 billion in cash, cash equivalents, and marketable securities.

Total Revenue
$93.4M
Previous year: $79.1M
+18.2%
EPS
-$1.27
Previous year: -$1.11
+14.4%
Gross Profit
$72.3M
Previous year: $62.4M
+15.9%
Cash and Equivalents
$461M
Previous year: $487M
-5.3%
Free Cash Flow
-$185M
Previous year: -$139M
+32.6%
Total Assets
$2.05B
Previous year: $1.32B
+55.0%

Insmed

Insmed

Forward Guidance

Insmed reiterates its full-year 2024 global ARIKAYCE revenues guidance in the range of $340 million to $360 million, representing 15% year-over-year growth at the midpoint compared to 2023.

Positive Outlook

  • Commercialization and continued growth of ARIKAYCE in its current indication globally.
  • Advancement of the clinical trial program intended to potentially support label expansion to include all patients with a MAC lung infection.
  • Satisfaction of the post-marketing requirement for full approval of ARIKAYCE's current indication.
  • Advancement of brensocatib, including activities related to regulatory filing and commercial launch readiness for bronchiectasis.
  • Ongoing Phase 2 BiRCh trial in patients with CRSsNP and the anticipated Phase 2 program in HS.

Challenges Ahead

  • Failure to continue to successfully commercialize ARIKAYCE.
  • Inability to obtain full approval of ARIKAYCE from the FDA.
  • Failure to obtain regulatory approvals for brensocatib, TPIP, or other product candidates.
  • Uncertainties in market acceptance of ARIKAYCE or brensocatib or TPIP.
  • Inability to obtain and maintain adequate reimbursement from government or third-party payors.