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Dec 31, 2021

Ironwood Pharmaceuticals Q4 2021 Earnings Report

Reported fourth quarter and full year 2021 results, with LINZESS® achieving blockbuster status.

Key Takeaways

Ironwood Pharmaceuticals reported strong Q4 2021 results, driven by the success of LINZESS® which achieved blockbuster status with over $1 billion in U.S. net sales for the year. The company is also advancing its GI pipeline with clinical studies for IW-3300 and CNP-104.

LINZESS® achieved blockbuster status with over $1 billion in U.S. net sales in 2021.

Initiated clinical studies for IW-3300 for visceral pain conditions.

Initiated clinical study for CNP-104 for primary biliary cholangitis (PBC).

Company focuses on maximizing LINZESS growth and strengthening the GI pipeline.

Total Revenue
$117M
Previous year: $117M
+0.4%
EPS
$0.27
Previous year: $0.36
-25.0%
Gross Profit
$117M
Previous year: $116M
+0.9%
Cash and Equivalents
$620M
Previous year: $363M
+70.8%
Free Cash Flow
$64.4M
Previous year: $51.5M
+25.2%
Total Assets
$1.13B
Previous year: $559M
+101.5%

Ironwood Pharmaceuticals

Ironwood Pharmaceuticals

Forward Guidance

Ironwood anticipates continued growth for LINZESS and aims to strengthen its GI pipeline while delivering sustained profits and generating cash flow.

Positive Outlook

  • Maximizing LINZESS growth via commercial innovation and lifecycle management.
  • Strengthening innovative GI pipeline.
  • Delivering sustained profits.
  • Generating cash flow.
  • Advancing the treatment of GI diseases.

Challenges Ahead

  • Effectiveness of development and commercialization efforts by Ironwood and its partners.
  • Preclinical and clinical development, manufacturing and formulation development of linaclotide, CNP-104 and Ironwood's product candidates.
  • Risk that clinical programs and studies may not progress or develop as anticipated.
  • Risk that Ironwood or its partners are unable to obtain, maintain or manufacture sufficient LINZESS or product candidates.
  • Efficacy, safety and tolerability of linaclotide and Ironwood's product candidates.