Dec 31, 2024

Intra-Cellular Q4 2024 Earnings Report

Intra-Cellular Therapies reported a net loss for Q4 2024, with CAPLYTA net product sales increasing by 51% compared to the same period in 2023.

Key Takeaways

Intra-Cellular Therapies reported Q4 2024 financial results, featuring a 51% increase in CAPLYTA net product sales to $199.2 million compared to the same period in 2023. The FDA accepted the sNDA submission for lumateperone for adjunctive treatment of major depressive disorder (MDD).

CAPLYTA net product sales grew to $199.2 million in Q4 2024, a 51% increase year-over-year.

The FDA accepted the lumateperone sNDA submission for adjunctive treatment of MDD.

Patient enrollment commenced in two Phase 3 studies in pediatric patients for the treatment of irritability associated with autism spectrum disorder.

Cash, cash equivalents, investment securities, and restricted cash totaled $1.0 billion on December 31, 2024.

Total Revenue
$199M
Previous year: $132M
+50.8%
EPS
-$0.16
Previous year: -$0.3
-46.7%
Cash and Equivalents
$307M
Previous year: $148M
+107.7%
Total Assets
$1.37B
Previous year: $728M
+87.7%

Intra-Cellular

Intra-Cellular

Forward Guidance

Intra-Cellular Therapies anticipates potential approval of CAPLYTA for adjunctive treatment of MDD and is expanding its field sales force.

Positive Outlook

  • Potential approval of CAPLYTA for adjunctive treatment of MDD.
  • Expansion of field sales force in anticipation of potential approval of CAPLYTA for MDD.
  • Ongoing patient enrollment in Phase 3 studies for pediatric patients with autism spectrum disorder.
  • Advancing ITI-1549 IND enabling studies.
  • Patient enrollment ongoing in Phase 2 clinical studies evaluating ITI-1284 in patients with generalized anxiety disorder (GAD).

Challenges Ahead

  • There is no guarantee we will complete the pending transaction with Johnson & Johnson within the timeframe we anticipate or at all.
  • Challenges associated with execution of our sales activities, which in each case could limit the potential of our product.
  • There is no guarantee that a generic equivalent of CAPLYTA will not be approved and enter the market before the expiration of our patents.
  • There is no guarantee that our sNDA for the adjunctive treatment of MDD will be approved, if at all, on the timeline that we expect.
  • Our other product candidates may not be successful or may take longer and be more costly than anticipated.