Lifecore Biomedical experienced a 4% decrease in Q4 2025 revenue to $36.4 million, primarily due to lower CDMO development revenue, though HA manufacturing revenue increased. The company significantly reduced its net loss to $1.1 million from $7.1 million in the prior year, driven by a gain from a legacy business obligation settlement and favorable debt derivative adjustment. For the full fiscal year, revenue reached $128.9 million, meeting guidance, but the company reported a net loss of $38.7 million.
Fourth-quarter revenue decreased by 4% to $36.4 million, primarily due to a $5.6 million decrease in CDMO revenues, partially offset by a $4.1 million increase in HA manufacturing revenues.
Net loss for Q4 significantly improved to $1.1 million ($0.06 per diluted share) from $7.1 million ($0.19 per diluted share) in the prior year, benefiting from a legacy business obligation settlement and a favorable debt derivative adjustment.
Adjusted EBITDA for Q4 was $9.1 million, a decrease of $1.3 million compared to $10.4 million in the prior year period, mainly due to lower gross profit.
The company signed three new early-stage programs in Q4 2025, including one with a large multinational pharmaceutical company, and a total of nine new programs with new customers for the fiscal year, expanding into new modalities.
For the approximately seven-month transition period from May 26 to December 31, 2025, Lifecore expects revenue to be between $74 million and $76 million, with an estimated net loss ranging from $19.8 million to $17.8 million, and Adjusted EBITDA between $12 million and $14 million.
Visualization of income flow from segment revenue to net income