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Dec 31, 2024

Leap Therapeutics Q4 2024 Earnings Report

Leap Therapeutics reported its Q4 2024 results, highlighting increased R&D expenses and continued net losses, with clinical progress for sirexatamab.

Key Takeaways

The company reported no revenue for Q4 2024 and recorded higher research and development expenses year-over-year, contributing to a net loss of $15.4 million for the quarter. Leap continued advancing its clinical programs, with positive data from the DeFianCe study supporting future registrational trials.

Leap reported no revenue for Q4 2024.

R&D expenses for Q4 2024 increased to $13.1 million from $11.7 million in Q4 2023.

General and administrative expenses totaled $3.0 million for the quarter, slightly down from $3.1 million last year.

Net loss for Q4 2024 was $15.4 million, compared to $12.5 million in Q4 2023.

Total Revenue
$0
Previous year: $634K
-100.0%
EPS
-$0.37
Previous year: -$0.46
-19.6%
R&D Expenses
$13.1M
Previous year: $11.7M
+12.2%
G&A Expenses
$3.01M
Previous year: $3.14M
-3.9%
Cash and Equivalents
$47.2M
Previous year: $70.6M
-33.1%
Total Assets
$49.1M
Previous year: $72.8M
-32.5%

Leap Therapeutics

Leap Therapeutics

Forward Guidance

Leap Therapeutics plans to leverage positive Phase 2 data to advance sirexatamab into registrational studies while continuing preclinical development of FL-501.

Positive Outlook

  • Strong positive data from the DeFianCe study supports Phase 3 planning.
  • Targeting large market opportunities in colorectal cancer treatment.
  • Pipeline advancement with upcoming FL-501 data presentations.
  • Cash position of $47.2 million to support ongoing operations.
  • Engagement with financial advisors to explore partnerships and development opportunities.

Challenges Ahead

  • Continued quarterly net losses and no current revenue.
  • High R&D and operational expenses impacting profitability.
  • Dependence on successful trial results and regulatory approvals.
  • Market and funding uncertainties could impact future development.
  • Potential dilution concerns with continued financing needs.