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Jun 30, 2023

Lyra Q2 2023 Earnings Report

Lyra Therapeutics reported financial results for the second quarter ended June 30, 2023 and provided a corporate update.

Key Takeaways

Lyra Therapeutics reported a net loss of $15.6 million for the second quarter of 2023. The company's cash, cash equivalents, and short-term investments totaled $116.2 million as of June 30, 2023, which is expected to fund operations into the first quarter of 2025. The company is advancing its clinical programs for LYR-210 and LYR-220.

Enrollment in the ENLIGHTEN I pivotal trial of LYR-210 is expected to complete in the coming weeks, with data expected in the first half of 2024.

Initial topline results from the BEACON Phase 2 trial of LYR-220 are anticipated in September 2023.

A private placement in May 2023 resulted in net proceeds of $46.7 million.

Cash, cash equivalents and short-term investments as of June 30, 2023 were $116.2 million.

Total Revenue
$458K
Previous year: $407K
+12.5%
EPS
-$0.36
Previous year: -$0.43
-16.3%
Gross Profit
-$10.3M
Previous year: $107K
-9764.5%
Cash and Equivalents
$54.4M
Previous year: $121M
-55.0%
Free Cash Flow
-$14.4M
Previous year: -$8.48M
+69.2%
Total Assets
$126M
Previous year: $130M
-3.4%

Lyra

Lyra

Forward Guidance

Lyra Therapeutics anticipates completing enrollment in the ENLIGHTEN I pivotal trial and reporting initial topline results from the BEACON Phase 2 trial. The company expects its cash balance to fund operations into the first quarter of 2025.

Positive Outlook

  • Completion of enrollment in ENLIGHTEN I trial expected soon.
  • Initial topline results from BEACON Phase 2 trial expected in September 2023.
  • Cash balance sufficient to fund operations into Q1 2025.
  • Advancing in-house manufacturing capabilities.
  • LYR-210 data expected in the first half of 2024.

Challenges Ahead

  • Incurred significant losses since inception and expects to incur additional losses for the foreseeable future.
  • Need for additional funding, which may not be available.
  • Limited operating history and no approved products.
  • Product candidates are in various stages of development.
  • Never scaled up an in-house manufacturing facility for clinical or commercial use.