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Dec 31, 2023

Lyra Q4 2023 Earnings Report

Reported financial results for Q4 and full year 2023 and provided a corporate update.

Key Takeaways

Lyra Therapeutics reported its Q4 and full year 2023 financial results, highlighting upcoming milestones for their product candidates LYR-210 and LYR-220, including topline results from the ENLIGHTEN I Phase 3 trial expected in Q2 2024. The company's cash runway is projected into the first quarter of 2025.

Topline results from ENLIGHTEN I pivotal Phase 3 clinical trial of LYR-210 are expected in Q2 2024.

Enrollment in ENLIGHTEN II, the second pivotal Phase 3 clinical trial of LYR-210, is expected to be completed in the second half of 2024.

Results from ENLIGHTEN I 52-week extension study are expected in Q4 2024.

An end-of-Phase 2 meeting for LYR-220 with the FDA is scheduled for the second half of 2024.

Total Revenue
$146K
Previous year: $11K
+1227.3%
EPS
-$0.22
Previous year: -$0.32
-31.3%
Gross Profit
$61K
Previous year: -$211K
-128.9%
Cash and Equivalents
$22.4M
Previous year: $32.6M
-31.3%
Free Cash Flow
-$19.8M
Previous year: -$12.2M
+62.8%
Total Assets
$143M
Previous year: $110M
+29.7%

Lyra

Lyra

Forward Guidance

Lyra Therapeutics anticipates several milestones in 2024, focusing on clinical trial results and regulatory interactions.

Positive Outlook

  • Reporting topline results from ENLIGHTEN I pivotal Phase 3 clinical trial of LYR-210 in Q2 2024.
  • Completing enrollment in ENLIGHTEN II, the second pivotal Phase 3 clinical trial of LYR-210, in the second half of 2024.
  • Reporting results from ENLIGHTEN I 52-week extension study in Q4 2024.
  • Having an end of Phase 2 meeting for LYR-220 with the U.S. Food and Drug Administration (FDA) in the second half of 2024.
  • Management believes its existing cash, cash equivalents and short-term investments balance are sufficient to fund the Company’s planned operations into the first quarter of 2025.