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Mar 31, 2025
MacroGenics Q1 2025 Earnings Report
MacroGenics reported its financial results for the first quarter of 2025, showing a decrease in net loss and an increase in total revenue compared to the same period last year.
Key Takeaways
MacroGenics, Inc. reported a net loss of $41.036 million for the first quarter of 2025, an improvement from the $52.190 million net loss in the first quarter of 2024. Total revenue increased to $13.192 million from $9.104 million in the prior year, driven by collaborative and contract manufacturing agreements, partially offset by the sale of MARGENZA global rights.
Net loss decreased to $41.036 million in Q1 2025 from $52.190 million in Q1 2024.
Total revenue increased by 45% to $13.192 million in Q1 2025, up from $9.104 million in Q1 2024.
Research and development expenses decreased by 14% to $39.698 million in Q1 2025.
Selling, general and administrative expenses decreased to $10.718 million in Q1 2025, primarily due to lower stock-based compensation and reduced professional fees.
Revenue by Segment
Revenue by Geographic Location
Forward Guidance
MacroGenics anticipates its current cash, cash equivalents, and marketable securities, combined with projected future payments from partners, will fund operating plans into the second half of 2026. The company expects to continue incurring research and development expenses as it advances its pipeline.
Positive Outlook
- Anticipated future payments from partners will support cash runway.
- Ability to raise additional capital through capital markets or corporate partnerships, equity offerings, debt financings, collaborations, licensing arrangements or asset sales.
- Continued development of product candidates, including lorigerlimab, MGC026, and MGC028.
- Ongoing collaborations with global biopharmaceutical companies provide non-dilutive funding.
- Implementation of cost-saving measures designed to extend financial runway.
Challenges Ahead
- Uncertainty in realizing expectations and beliefs, with actual results potentially differing materially from forward-looking statements.
- Potential for delays, scope reduction, or elimination of product research and development programs if unable to secure additional capital or new arrangements.
Historical Earnings Impact
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Avg. Return Before/After Earnings
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