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Dec 31, 2021

Marinus Pharmaceuticals Q4 2021 Earnings Report

Marinus Pharmaceuticals reported financial results for the fourth quarter and the year ended December 31, 2021, and provided a business update, highlighting the FDA approval of ZTALMY® for CDKL5 deficiency disorder.

Key Takeaways

Marinus Pharmaceuticals announced the FDA approval of ZTALMY® for CDKL5 deficiency disorder and reported financial results for Q4 and full year 2021. The company is focused on expanding the clinical development of ganaxolone across various seizure disorders and preparing for commercialization.

ZTALMY® received FDA approval for the treatment of seizures associated with CDKL5 deficiency disorder (CDD).

The approval validates clinical development plans for ganaxolone as a treatment option for seizure disorders.

Marinus is developing a second-generation ganaxolone formulation to improve pharmacokinetic characteristics.

The company is preparing for commercialization of ZTALMY®.

Total Revenue
$1.52M
Previous year: $1.55M
-1.7%
EPS
-$0.77
Previous year: -$0.55
+40.0%
Gross Profit
-$16.5M
Previous year: -$10.9M
+51.3%
Cash and Equivalents
$123M
Previous year: $140M
-12.2%
Total Assets
$137M
Previous year: $150M
-9.1%

Marinus Pharmaceuticals

Marinus Pharmaceuticals

Forward Guidance

Marinus Pharmaceuticals faces several opportunities and challenges in the development and commercialization of ganaxolone.

Positive Outlook

  • Potential for significant non-dilutive funding due to ZTALMY approval.
  • Expansion of ganaxolone's therapeutic utility through new formulations.
  • Advancement of clinical development plans across various seizure disorders.
  • Opportunity to build commercial infrastructure and capabilities.
  • Potential for positive clinical trial results to support regulatory approval and further development.

Challenges Ahead

  • Uncertainties and delays in clinical trial design, enrollment, and completion.
  • Potential for regulatory authorities to delay or deny approval of product candidates.
  • Risk of unanticipated costs and expenses.
  • Dependence on third-party patents and potential negative impact on commercialization.
  • Risk of delays, interruptions, or failures in the manufacture and supply of product candidates.