Nurix Therapeutics reported collaboration revenue of $6.8 million for the quarter and a net loss of $46.7 million, or ($0.87) per share. The company's cash, cash equivalents and marketable securities totaled $373.0 million as of November 30, 2022.
NX-2127 overcomes BTK inhibitor resistance mutations and provides clinical benefit to patients with hematological malignancies
Achieved significant milestones in wholly owned clinical programs and partnered preclinical programs
Maintained strong financial position with year-end cash and marketable securities totaling $373 million
Presented multiple posters highlighting data from Nurix’s Casitas B-lineage lymphoma proto-oncogene (CBL-B) inhibitor programs at the Society for Immunotherapy of Cancer (SITC) Annual Meeting
Nurix anticipates presenting additional clinical results for NX-2127 in the second half of 2023 and defining a regulatory strategy based on emerging clinical data and FDA feedback. Initial clinical data from the Phase 1a portion of the NX-5948 study is expected in the second half of 2023, with a dose defined for Phase 1b cohort expansion. Clinical data from the Phase 1a portion of the NX-1607 study is expected in the second half of 2023, with a dose defined for Phase 1b cohort expansion. Nurix expects to select a new targeted protein degrader development candidate in 2023 and continue to achieve substantial research collaboration milestones throughout 2023 with Gilead Sciences and Sanofi.