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Nov 30, 2024

Nurix Q4 2024 Earnings Report

Reported financial results for the fourth quarter and fiscal year ended November 30, 2024, and provided a corporate update.

Key Takeaways

Nurix Therapeutics reported Q4 revenue of $13.3 million and a net loss of $58.5 million, or ($0.75) per share. The company's cash, cash equivalents, and marketable securities totaled $609.6 million as of November 30, 2024.

Reported a robust objective response rate of 75.5% from the Phase 1 study of NX-5948 in patients with relapsed/refractory CLL/SLL.

Received PRIME designation from the European Medicines Agency for NX-5948 in CLL.

Received Fast Track designation from the U.S. FDA for NX-5948 in Waldenstrom’s Macroglobulinemia.

Announced the appointment of John Northcott as Chief Commercial Officer.

Total Revenue
$13.3M
Previous year: $15.2M
-12.4%
EPS
-$0.75
Previous year: -$0.77
-2.6%
Gross Profit
$13.3M
Previous year: $11.4M
+16.5%
Cash and Equivalents
$110M
Previous year: $54.6M
+101.4%
Free Cash Flow
-$50.9M
Previous year: $19.2M
-365.4%
Total Assets
$669M
Previous year: $356M
+88.2%

Nurix

Nurix

Nurix Revenue by Segment

Forward Guidance

Nurix plans to commence a suite of clinical trials designed to support global registration of NX-5948 for the treatment of patients with CLL and to explore its development in inflammatory diseases.

Positive Outlook

  • Plans to commence a suite of clinical trials designed to support global registration of NX-5948 for the treatment of patients with CLL.
  • Exploring development of NX-5948 in inflammatory diseases.
  • Initiating clinical testing of NX-5948 in autoimmune cytopenias in 2025.
  • Advancing a pipeline of wholly owned and partnered programs in inflammation and immunology.
  • Expecting clinical updates in patients with both CLL and non-Hodgkin’s lymphoma in 2025.

Challenges Ahead

  • Uncertainties related to the timing and results of preclinical studies and clinical trials.
  • Whether Nurix will be able to fund development activities and achieve development goals.
  • Uncertainties related to the timing and receipt of payments from Nurix’s collaboration partners.
  • The impact of global business, political and macroeconomic conditions on Nurix’s business.
  • Whether Nurix will be able to protect intellectual property.