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Jun 30, 2023

Olema Q2 2023 Earnings Report

Reported financial results for the second quarter ended June 30, 2023, and provided a corporate update.

Key Takeaways

Olema Oncology reported a net loss of $20.1 million for the second quarter ended June 30, 2023, compared to a net loss of $32.9 million for the same period of the prior year. Cash, cash equivalents and marketable securities were $167.4 million as of June 30, 2023, expected to fund operations into the second quarter of 2025.

Initiation of OPERA-01 pivotal Phase 3 monotherapy clinical trial on track; expecting to enroll first patient in fourth quarter.

New clinical data for palazestrant (OP-1250) to be presented in the fourth quarter including both monotherapy and CDK4/6 inhibitor combination updates.

Cash, cash equivalents and marketable securities of $167.4 million as of June 30, 2023, expected to fund operations into the second quarter of 2025.

Presented interim Phase 1b/2 clinical study results of palazestrant in combination with a CDK4/6 inhibitor (palbociclib) at the 2023 European Society for Medical Oncology (ESMO) Breast Cancer Annual Congress in Berlin, Germany.

EPS
-$0.49
Previous year: -$0.82
-40.2%
Cash and Equivalents
$167M
Previous year: $241M
-30.4%
Total Assets
$178M
Previous year: $251M
-29.1%

Olema

Olema

Forward Guidance

Olema expects to deliver on significant milestones this year, including initiating OPERA-01 Phase 3 trial, and presenting new data from ongoing monotherapy and combination clinical studies.

Positive Outlook

  • Initiate OPERA-01, Olema’s first pivotal Phase 3 clinical trial, testing palazestrant as a monotherapy in second- and third-line metastatic breast cancer, anticipated in the fourth quarter of 2023.
  • Present palazestrant interim Phase 1b clinical study results in combination with CDK4/6 inhibitor, ribociclib, in the fourth quarter of 2023.
  • Present palazestrant interim Phase 1b/2 clinical study results in combination with CDK4/6 inhibitor, palbociclib, in the fourth quarter of 2023.
  • Present palazestrant Phase 2 monotherapy clinical study results as an oral presentation at the European Society for Medical Oncology (ESMO) Congress 2023 in Madrid, Spain, on October 22, 2023.
  • Olema anticipates that cash balance will be sufficient to fund operations into the second quarter of 2025.