•
Sep 30, 2022

Omega Therapeutics Q3 2022 Earnings Report

Omega Therapeutics' financial performance and corporate developments were reported for Q3 2022.

Key Takeaways

Omega Therapeutics reported a net loss of $25.8 million for the third quarter of 2022, driven by increased R&D and G&A expenses. The company's cash, cash equivalents, and marketable securities totaled $148.3 million as of September 30, 2022. Key highlights included the first patient dosed in the Phase 1/2 MYCHELANGELO I trial of OTX-2002 and the selection of OTX-2101 for MYC-Driven Non-Small Cell Lung Cancer as a second development candidate.

First patient dosed in Phase 1/2 MYCHELANGELO I Trial of OTX-2002.

OTX-2002 granted Orphan Drug Designation by U.S. FDA for the treatment of Hepatocellular Carcinoma.

OTX-2101 for MYC-Driven Non-Small Cell Lung Cancer selected as second Omega Epigenomic Controllerâ„¢ Development Candidate.

Company had $148.3 million in cash, cash equivalents and marketable securities as of September 30, 2022.

Total Revenue
$595K
EPS
-$0.54
Previous year: -$0.57
-5.3%
G&A Expenses
$5.2M
Gross Profit
-$726K
Cash and Equivalents
$76.6M
Previous year: $234M
-67.3%
Free Cash Flow
-$25.2M
Previous year: -$16.8M
+49.3%
Total Assets
$170M
Previous year: $243M
-30.1%

Omega Therapeutics

Omega Therapeutics

Forward Guidance

This press release contains forward-looking statements regarding the timing and design of clinical trials, the potential of the OMEGA platform, expectations surrounding product candidates, and expectations regarding the pipeline.

Positive Outlook

  • The Phase 1/2 MYCHELANGELOTM I clinical trial is ongoing.
  • The OMEGA platform has the potential to engineer programmable epigenetic mRNA therapeutics.
  • Product candidates like OTX-2002 and OTX-2101 show potential.
  • The company is advancing multiple preclinical development programs.
  • The company is working on treatments for oncology, immunology, regenerative medicine, and select monogenic diseases.

Challenges Ahead

  • The novel technology makes it difficult to predict the time and cost of development.
  • There are substantial development and regulatory risks associated with epigenomic controller machines.
  • The company has a limited operating history and expects to incur significant additional losses.
  • Preclinical development is uncertain, especially for a new class of medicines.
  • Product candidates may be associated with serious adverse events or undesirable side effects.