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Sep 30, 2021

Outlook Therapeutics Q4 2021 Earnings Report

Reported financial results for fiscal year 2021 and provided a corporate update.

Key Takeaways

Outlook Therapeutics reported a net loss attributable to common stockholders of $53.2 million for the fiscal year ended September 30, 2021. The company had cash and cash equivalents of $14.5 million at the end of the fiscal year and completed a $57.5 million gross proceeds equity offering subsequent to the fiscal year end.

Successfully completed the registration clinical trials for ONS-5010.

Reported statistically significant and clinically relevant data from clinical trials.

Plans to submit a new BLA under the Public Health Service Act (PHSA) 351(a) regulatory pathway in the first quarter of calendar 2022.

Began commercial launch planning for ONS-5010, including manufacturing, distribution, sales force planning, and engagement with physicians and payors.

EPS
-$1.6
Previous year: -$0.6
+166.7%
Cash and Equivalents
$14.5M
Previous year: $12.5M
+16.0%
Total Assets
$44.8M
Previous year: $19.7M
+127.0%

Outlook Therapeutics

Outlook Therapeutics

Forward Guidance

Outlook Therapeutics anticipates potential FDA approval in 2022 for ONS-5010 and expects to initiate registration clinical trials for ONS-5010 for DME and BRVO in 2023 if FDA approval is received for the wet AMD indication.

Positive Outlook

  • Potential FDA approval of ONS-5010 in the first quarter of calendar 2023, resulting in 12 years of marketing exclusivity.
  • Plans to file a supplementary application for approval to provide the product in a pre-filled, silicone-free syringe.
  • Collaborative discussions with payors and the retina community commenced.
  • Developing registration documents for approvals in Europe.
  • Exploring potential strategic commercialization partners.

Challenges Ahead

  • Risks associated with developing pharmaceutical product candidates.
  • Risks of conducting clinical trials.
  • Risks in obtaining necessary regulatory approvals.
  • Uncertainty of future impacts related to the ongoing COVID-19 pandemic.
  • Potential delays in clinical trials