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Mar 31, 2022

Vaxcyte Q1 2022 Earnings Report

Vaxcyte reported financial results for the first quarter ended March 31, 2022 and provided a business update.

Key Takeaways

Vaxcyte reported cash, cash equivalents and investments of $352.3 million as of March 31, 2022. The company's net loss was $39.0 million for the three months ended March 31, 2022.

Dosed First Participants in both the Phase 1 and Phase 2 Portions of Ongoing VAX-24 Phase 1/2 Clinical Proof-of-Concept Study in Adults

Completed Successful $115 Million Follow-On Financing

Appointed Mikhail Eydelman as Senior Vice President, General Counsel & Corporate Secretary

Vaxcyte expects to announce topline safety, tolerability and immunogenicity results from both the Phase 1 and Phase 2 portions of the Phase 1/2 clinical study evaluating VAX-24 for the prevention of invasive pneumococcal disease (IPD) and pneumonia in adults by the end of 2022.

EPS
-$0.68
Previous year: -$0.41
+65.9%
R&D Expenses
$31.7M
Previous year: $17.3M
+83.7%
G&A Expenses
$7.5M
Previous year: $5.89M
+27.4%
Cash and Equivalents
$352M
Previous year: $371M
-5.0%
Free Cash Flow
-$30.6M
Total Assets
$403M
Previous year: $382M
+5.3%

Vaxcyte

Vaxcyte

Forward Guidance

Vaxcyte anticipates several key milestones for its vaccine candidates.

Positive Outlook

  • Topline safety, tolerability and immunogenicity results from both the Phase 1 and Phase 2 portions of the Phase 1/2 clinical study evaluating VAX-24 for the prevention of invasive pneumococcal disease (IPD) and pneumonia in adults by the end of 2022.
  • Enrollment in a separate Phase 2 study of approximately 200 healthy adults aged 65 and older in mid-2022 to evaluate the safety, tolerability and immunogenicity of a single injection of VAX-24.
  • Topline results from the Phase 2 study in adults aged 65 and older are expected to be announced in the first half of 2023.
  • Submission of its first VAX-24 pediatric Investigational New Drug (IND) application to the U.S. Food and Drug Administration (FDA) in the first half of 2023.
  • Guidance for the anticipated submission of its IND application in adults to the FDA following the announcement of the topline results from the ongoing VAX-24 Phase 1/2 study in adults aged 18 to 64 for VAX-XP.