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Mar 31, 2024

Vaxcyte Q1 2024 Earnings Report

Vaxcyte reported financial results for Q1 2024 and provided a business update, highlighting the completion of enrollment in the VAX-31 adult Phase 1/2 study and the VAX-24 infant Phase 2 study.

Key Takeaways

Vaxcyte reported a net loss of $95.0 million for the first quarter of 2024. The company's cash, cash equivalents, and investments totaled $1,899.8 million as of March 31, 2024, including $816.5 million in net proceeds from a February public offering. Enrollment was completed in both the VAX-31 adult Phase 1/2 study and the VAX-24 infant Phase 2 study.

Completed enrollment of Phase 1/2 study evaluating VAX-31 for the prevention of IPD in adults aged 50 and older.

Completed enrollment of Phase 2 study evaluating VAX-24 for the prevention of IPD in infants.

Completed successful $862.5 million follow-on financing.

Anticipates topline safety, tolerability and immunogenicity data from VAX-31 adult Phase 1/2 study in Q3 2024.

Total Revenue
$0
EPS
-$0.85
Previous year: -$0.7
+21.4%
R&D Expenses
$94.6M
Previous year: $58.1M
+62.8%
G&A Expenses
$19.9M
Previous year: $13.1M
+51.8%
Gross Profit
-$3.09M
Cash and Equivalents
$1.9B
Previous year: $950M
+100.0%
Free Cash Flow
-$165M
Previous year: -$53.3M
+209.2%
Total Assets
$1.5B
Previous year: $1.01B
+48.4%

Vaxcyte

Vaxcyte

Forward Guidance

Vaxcyte is advancing the clinical development of its PCV programs with several anticipated key upcoming milestones.

Positive Outlook

  • Announce topline safety, tolerability and immunogenicity data from VAX-31 adult Phase 1/2 study in the third quarter of 2024.
  • Following VAX-31 data, advance either VAX-24 or VAX-31 to an adult Phase 3 program.
  • Initiate Phase 3 pivotal, non-inferiority study in adults aged 50 and older in the second half of 2024 and announce topline safety, tolerability and immunogenicity data in the second half of 2025 if VAX-24 is advanced.
  • Initiate balance of expected Phase 3 studies in 2025 and 2026 if VAX-24 is advanced.
  • Initiate full complement of expected Phase 3 studies in 2025 and 2026 if VAX-31 is advanced.