Dec 31, 2021

Phathom Q4 2021 Earnings Report

Phathom Pharmaceuticals reported a net loss for Q4 2021 and highlighted pipeline and business progress.

Key Takeaways

Phathom Pharmaceuticals reported a net loss of $35.8 million for the fourth quarter of 2021, driven by a net loss from operations of $33.0 million. Research and development expenses decreased to $13.5 million, while general and administrative expenses increased to $19.5 million.

Net loss for Q4 2021 was $35.8 million, compared to $53.7 million for Q4 2020.

Net loss from operations for Q4 2021 was $33.0 million, including a $4.3 million non-cash charge related to stock-based compensation.

Research and development expenses decreased to $13.5 million in Q4 2021, compared to $41.6 million in Q4 2020.

General and administrative expenses increased to $19.5 million in Q4 2021, compared to $10.8 million in Q4 2020, due to the buildout of the commercial function.

EPS
-$0.95
Previous year: -$1.58
-39.9%
Cash and Equivalents
$183M
Previous year: $287M
-36.3%
Free Cash Flow
-$41.5M
Total Assets
$189M
Previous year: $295M
-35.8%

Phathom

Phathom

Forward Guidance

Phathom anticipates an NDA submission for erosive esophagitis in March 2022, FDA approval of vonoprazan-based regimens for H. pylori treatment by May 3, 2022, a U.S. launch of vonoprazan for H. pylori in the second half of 2022, and enrollment completion of a Phase 3 NERD trial in the second half of 2022.

Positive Outlook

  • NDA submission for erosive esophagitis (EE) in March 2022.
  • FDA approval of vonoprazan-based regimens for H. pylori infection expected by May 3, 2022.
  • U.S. launch of vonoprazan for treatment of H. pylori in second half of 2022.
  • Enrollment completion of Phase 3 non-erosive reflux disease (NERD) daily dosing trial in the second half of 2022.