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Mar 31, 2023

Protagonist Q1 2023 Earnings Report

Reported positive topline results from Phase 2b FRONTIER 1 study and Phase 2 REVIVE study, and extended cash runway through end of 2025.

Key Takeaways

Protagonist Therapeutics reported positive topline data from the Phase 2b FRONTIER 1 study of JNJ-2113 and the Phase 2 REVIVE study of rusfertide. They also extended their cash runway through the end of 2025 with a public offering.

Announced positive topline results from the Phase 2b FRONTIER 1 study of JNJ-2113 for moderate-to-severe plaque psoriasis.

Announced positive topline results from the randomized withdrawal portion of the Phase 2 REVIVE study of rusfertide in polycythemia vera (PV).

Extended cash runway through end of 2025 with the completion of an underwritten public offering, resulting in net proceeds of $108.1 million.

Rusfertide's Phase 2 data supports its potential to provide meaningful benefit in hematocrit control, reduction in phlebotomy burden, and symptoms management for polycythemia vera patients.

EPS
-$0.67
Previous year: -$0.43
+55.8%
Cash and Equivalents
$108M
Previous year: $98.5M
+9.8%
Free Cash Flow
-$34.4M
Previous year: -$37.9M
-9.4%
Total Assets
$240M
Previous year: $348M
-31.1%

Protagonist

Protagonist

Forward Guidance

Protagonist Therapeutics anticipates that cash resources will fund discovery and clinical development initiatives, including the ongoing Phase 3 VERIFY study of rusfertide in PV through to its completion and New Drug Application filing.