•
Mar 31, 2024

Protagonist Q1 2024 Earnings Report

Protagonist reported financial results for the first quarter ended March 31, 2024 and provided a corporate update.

Key Takeaways

Protagonist Therapeutics announced a transformational partnership with Takeda to develop and commercialize rusfertide, allowing reinvestment in peptide therapeutics and expansion of efforts to create a new pipeline. Enrollment is complete in both Phase 3 ICONIC LEAD and ICONIC TOTAL trials of JNJ-2113 in patients with moderate to severe psoriasis. The company expects to nominate an oral IL-17 antagonist development candidate by the end of 2024.

Entered into a worldwide license and collaboration agreement for rusfertide with Takeda.

Cash runway extended through Q4 2027.

Enrollment in both Phase 3 ICONIC LEAD and ICONIC TOTAL trials of JNJ-2113 in patients with moderate to severe psoriasis is now complete.

Expect to nominate a development candidate from oral IL-17 program by end of 2024.

Total Revenue
$255M
EPS
$3.26
Previous year: -$0.67
-586.6%
Gross Profit
$254M
Cash and Equivalents
$323M
Previous year: $108M
+198.5%
Free Cash Flow
-$27.7M
Previous year: -$34.4M
-19.5%
Total Assets
$629M
Previous year: $240M
+162.4%

Protagonist

Protagonist

Forward Guidance

The company expects to nominate an oral IL-17 antagonist development candidate this year from their internal discovery efforts, and anticipates results from the Phase 2b ANTHEM study in ulcerative colitis.