Protagonist Therapeutics reported second quarter 2024 financial results, highlighting advancements in rusfertide and JNJ-2113 clinical development, and the expansion of their discovery platform for oral peptides-based programs. The company also noted its addition to the S&P SmallCap 600® index.
Rusfertide's Phase 2 REVIVE trial data reaffirmed durable positive response in polycythemia vera.
Phase 3 VERIFY 32-week primary endpoint readout for rusfertide is expected in Q1 2025.
Rapid enrollment is ongoing in five Phase 3 trials of JNJ-2113 in psoriasis and a Phase 2b study in ulcerative colitis.
Primary endpoint portion of ICONIC-LEAD, ICONIC-TOTAL, and ANTHEM studies are expected to be completed this year.
Protagonist anticipates multiple new development candidates in various indications over the next 12 months and expects completion of primary endpoint portions for several Phase 3 trials of JNJ-2113 and the Phase 2b study in ulcerative colitis this year.