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Sep 30, 2023

uniQure Q3 2023 Earnings Report

uniQure announced its Q3 2023 financial results, highlighting FDA clearance of IND application for AMT-260, progress in clinical trials for AMT-130, and a strategic reorganization for cost savings.

Key Takeaways

uniQure reported Q3 2023 revenues of $1.4 million, consistent with the previous year. The company experienced a net loss of $89.6 million, compared to a $47.9 million loss in the same period of 2022. They announced FDA clearance for AMT-260 and are on track to provide a clinical update on AMT-130. A strategic reorganization is expected to save $180 million over three years, with a strong cash position of approximately $660 million.

Received FDA clearance for Investigational New Drug application for AMT-260 in refractory mesial temporal lobe epilepsy.

On track to provide a clinical update from U.S. and European Phase I/II trials of AMT-130 in Huntington’s disease later in the fourth quarter of 2023.

uniQure and CSL won the 2023 Prix Galien USA award for HEMGENIX®.

Announced a strategic reorganization expected to deliver $180 million of cost savings over the next three years.

Total Revenue
$1.41M
Previous year: $1.45M
-2.9%
EPS
-$1.88
Previous year: -$1.02
+84.3%
Gross Profit
-$2.2M
Previous year: $1.45M
-251.6%
Cash and Equivalents
$659M
Previous year: $440M
+49.6%
Free Cash Flow
$37.5M
Previous year: -$53M
-170.8%
Total Assets
$872M
Previous year: $638M
+36.6%

uniQure

uniQure

Forward Guidance

uniQure expects continued progress on HEMGENIX® commercialization, plans to announce follow-up data from AMT-130 trials, aims to submit an IND for AMT-191, and anticipates initiating patient screening for AMT-162 and AMT-260.

Positive Outlook

  • Continued progress on the commercialization of HEMGENIX®
  • Plans to announce follow up data from the U.S. and European Phase I/II clinical study of AMT-130 in 2023
  • Expectation to submit an investigational new drug application for AMT-191 in Fabry disease in 2023 and begin patient dosing in 2024
  • Expectation to initiate patient screening in AMT-162 and AMT-260 in the fourth quarter of 2023
  • Begin patient dosing in each in the first quarter of 2024

Challenges Ahead

  • Risks associated with the regulatory approval and commercial launch of HEMGENIX®
  • Material changes to our interim or preliminary data
  • Impact of financial and geopolitical events on our Company and the wider economy and health care system
  • Company’s ability to raise additional capital to support late stage development of the Company’s clinical program(s) if supported by future data
  • Risks, uncertainties and other factors described under the heading "Risk Factors" in the Company’s periodic securities filings