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Dec 31, 2021

uniQure Q4 2021 Earnings Report

uniQure reported financial results for 2021 and highlighted recent progress across its business.

Key Takeaways

uniQure reported a strong financial year, ending with $556.3 million in cash and cash equivalents. The company's revenue significantly increased due to the CSL Behring transaction and milestone payments. Net income was $329.6 million, a substantial improvement compared to the previous year's loss.

Ended 2021 with $556.3 million in cash and cash equivalents.

Revenue for the year was $524.0 million, driven by the CSL Behring transaction.

Net income for the year was $329.6 million, a significant increase from the previous year.

Advanced clinical-stage programs and expanded the research pipeline.

Total Revenue
$57.7M
Previous year: $34.1M
+69.3%
EPS
$0.17
Previous year: -$0.01
-1800.0%
Gross Profit
$55.9M
Previous year: $31.2M
+79.2%
Cash and Equivalents
$556M
Previous year: $245M
+127.2%
Free Cash Flow
-$50.6M
Previous year: -$40M
+26.7%
Total Assets
$809M
Previous year: $340M
+137.7%

uniQure

uniQure

Forward Guidance

uniQure is focused on maintaining momentum in enrolling Phase I/II studies in Huntington’s disease, sharing safety and biomarker data, advancing gene therapy product candidates for Fabry disease and refractory temporal lobe epilepsy, and expanding its manufacturing footprint.

Positive Outlook

  • Maintaining strong momentum in enrolling Phase I/II studies in Huntington’s disease.
  • Sharing additional safety and biomarker data from patients in the lower dose cohort.
  • Advancing gene therapy product candidates for Fabry disease and refractory temporal lobe epilepsy into IND-enabling toxicology studies.
  • Initiating at least two new gene therapy programs targeting the liver and CNS during the year.
  • Expanding manufacturing footprint with a second cGMP facility in Amsterdam.

Challenges Ahead

  • Risks associated with the impact of the ongoing COVID-19 pandemic.
  • Risks related to clinical development activities.
  • Risks related to clinical results.
  • Risks related to regulatory oversight.
  • Risks related to product commercialization and intellectual property claims.