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Mar 31

Regeneron Q1 2025 Earnings Report

Regeneron reported a revenue decline but maintained profitability in Q1 2025.

Key Takeaways

Regeneron faced a slight revenue decrease but achieved strong profitability driven by robust Dupixent sales and strategic pipeline advancements.

Total revenue was $3,028,700,000, a 4% decline YoY.

GAAP Net Income grew 12% to $808,700,000.

Adjusted EPS reached $8.22 despite lower non-GAAP net income.

Dupixent global net sales increased 19% to $3,665,600,000.

Total Revenue
$3.03B
Previous year: $3.15B
-3.7%
EPS
$8.22
Previous year: $9.55
-13.9%
Revenue Growth
-4%
GAAP Net Income Growth
12%
Non-GAAP Net Income
$928M
Gross Profit
$1.14B
Previous year: $2.6B
-56.1%
Cash and Equivalents
$17.6B
Previous year: $17.5B
+0.7%
Free Cash Flow
$816M
Total Assets
$37.5B
Previous year: $34.4B
+9.2%

Regeneron

Regeneron

Regeneron Revenue by Segment

Regeneron Revenue by Geographic Location

Forward Guidance

Regeneron maintained its 2025 guidance for R&D and SG&A spending while slightly lowering gross margin expectations.

Positive Outlook

  • Maintained R&D and SG&A spending guidance.
  • Capital expenditure guidance slightly lowered.
  • Non-GAAP effective tax rate guidance unchanged at 11%-13%.
  • Continued internal investment in clinical and commercial capabilities.
  • Ongoing share repurchases and dividend program boost shareholder value.

Challenges Ahead

  • Lowered GAAP gross margin outlook from 84%-85% to 83%-84%.
  • Non-GAAP gross margin outlook reduced from 87%-88% to 86%-87%.
  • EYLEA HD faced a Complete Response Letter (CRL) for pre-filled syringe.
  • Competition continues to pressure EYLEA sales volume and pricing.
  • Patient affordability challenges impact higher-cost anti-VEGF therapies.

Revenue & Expenses

Visualization of income flow from segment revenue to net income