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Dec 31, 2024
REGENXBIO Q4 2024 Earnings Report
REGENXBIO reported a decrease in revenue and a narrower net loss for Q4 2024.
Key Takeaways
REGENXBIO reported Q4 2024 revenue of $21.2 million, a slight decrease from the previous year, primarily due to lower royalty revenues. Net loss for the quarter improved to $51.2 million compared to $62.9 million in Q4 2023. The company ended the year with $244.9 million in cash and expects its cash runway to extend into the second half of 2026. R&D expenses were $50.4 million, reflecting continued investment in gene therapy programs.
Q4 2024 revenue was $21.2 million, down from $22.2 million in Q4 2023.
Net loss improved to $51.2 million, compared to $62.9 million in the prior year.
R&D expenses were $50.4 million, reflecting investment in gene therapy trials.
Cash, cash equivalents, and marketable securities totaled $244.9 million.
Revenue by Segment
Forward Guidance
REGENXBIO expects its cash position, combined with an upfront payment from Nippon Shinyaku, to fund operations into 2H 2026 while continuing development of gene therapy programs.
Positive Outlook
- Strong cash position of $244.9M with extended cash runway into 2H 2026.
- Continued progress in pivotal trials for RGX-202 and ABBV-RGX-314.
- BLA submission for RGX-121 completed, with potential approval in 2H 2025.
- Strategic partnership with Nippon Shinyaku brings $110M upfront payment.
- Decreased net loss compared to prior year due to controlled expenses.
Challenges Ahead
- Decline in revenue due to lower Zolgensma royalty payments.
- High R&D expenses continue to impact profitability.
- Future revenue growth is dependent on regulatory approvals and partnerships.
- Stock-based compensation and operational costs remain significant.
Historical Earnings Impact
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Avg. Return Before/After Earnings
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