Cartesian Therapeutics reported a net loss of $(77.4) million for the full year ended December 31, 2024, with total revenue of $38.913 million. The company ended the year with approximately $214.3 million in cash, cash equivalents, and restricted cash, which is expected to support operations into mid-2027.
Phase 3 AURORA trial of Descartes-08 in myasthenia gravis is on track to commence in 1H25.
Deep and durable responses were maintained over 12 months in Descartes-08-treated participants in the Phase 2b trial.
Phase 2 trial of Descartes-08 in systemic lupus erythematosus is ongoing with expected data readout in 2H25.
The company expects to initiate a Phase 2 pediatric basket trial of Descartes-08 in select autoimmune indications in 2H25.
Cartesian Therapeutics is focused on advancing its pipeline, with key milestones including the commencement of the Phase 3 AURORA trial for Descartes-08 in MG, preliminary data from the Phase 2 SLE trial, and initiation of a Phase 2 pediatric basket trial.