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Sep 30, 2024
Revolution Medicines Q3 2024 Earnings Report
Revolution Medicines' financial position remained strong while advancing clinical programs.
Key Takeaways
Revolution Medicines reported its Q3 2024 financial results, highlighting the progress of its clinical-stage RAS(ON) inhibitors, including RMC-6236 and RMC-9805, and the initiation of a Phase 3 pivotal trial for RMC-6236 in metastatic pancreatic cancer. The company's cash position remains strong, enabling operations into 2027.
Phase 3 pivotal trial underway evaluating RMC-6236 in patients with metastatic pancreatic ductal adenocarcinoma (PDAC).
First clinical results for RMC-9805 demonstrate encouraging safety, tolerability and antitumor activity in patients with PDAC harboring a KRAS G12D mutation.
Company on track to provide update on lung cancer programs in the fourth quarter of 2024.
Cash, cash equivalents and marketable securities were $1.55 billion as of September 30, 2024.
Forward Guidance
Revolution Medicines is reiterating projected full year 2024 GAAP net loss guidance of between $560 million and $600 million, which includes estimated non-cash stock-based compensation expense of between $70 million and $80 million. Based on the company’s current operating plan, the company projects current cash, cash equivalents and marketable securities can fund planned operations into 2027.
Positive Outlook
- Projected full year 2024 GAAP net loss guidance reiterated.
- Cash, cash equivalents and marketable securities can fund planned operations into 2027.
- Estimated non-cash stock-based compensation expense included in net loss guidance.
- Company is advancing its portfolio and R&D pipeline.
- Company plans to provide updated data from its ongoing study of RMC-6236 monotherapy in patients with NSCLC in the fourth quarter of 2024.
Challenges Ahead
- Projected full year 2024 GAAP net loss between $560 million and $600 million.
- The company is facing challenges associated with manufacturing drug products.
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