Mar 31

Sana Q1 2025 Earnings Report

Sana Biotechnology reported financial results for the first quarter of 2025.

Key Takeaways

Sana Biotechnology reported a net loss of $49.4 million for the first quarter of 2025, a significant improvement compared to the $107.5 million loss in the same period last year. The company ended the quarter with $104.7 million in cash, cash equivalents, and marketable securities, with an expected cash runway into 2026. Sana highlighted positive clinical data for its type 1 diabetes program and progress in its allogeneic CAR T and in vivo CAR T pipelines.

Net loss for Q1 2025 was $49.4 million, a substantial decrease from $107.5 million in Q1 2024.

Ended Q1 2025 with $104.7 million in cash, cash equivalents, and marketable securities.

Presented positive 12-week clinical data for UP421 in type 1 diabetes, showing immune evasion and continued function.

Advancing clinical trials for SC291 in autoimmune diseases and SC262 in B-cell malignancies, with data expected in 2025.

Total Revenue
$0
0
EPS
-$0.2
Previous year: -$0.32
-37.5%
Non-GAAP Operating Cash Burn
$46.6M
Previous year: $58.7M
-20.6%
Research and Development Expenses
$37.2M
Previous year: $56.4M
-34.1%
Weighted-Average Shares Outstanding
237.58M
Cash and Equivalents
$105M
Previous year: $311M
-66.3%
Total Assets
$445M
Previous year: $681M
-34.6%

Sana

Sana

Forward Guidance

Sana expects its current cash, cash equivalents, and marketable securities to provide a cash runway into 2026. The company anticipates filing INDs for SC451 in type 1 diabetes and SG299 in B-cell related diseases as early as 2026 and plans to report clinical data from the GLEAM and VIVID trials in 2025.

Positive Outlook

  • Expected cash runway into 2026.
  • Anticipate filing IND for SC451 in type 1 diabetes as early as 2026.
  • Anticipate filing IND for SG299 in B-cell related diseases as early as 2026.
  • Expect to report clinical data from the GLEAM trial (SC291 in autoimmune diseases) in 2025.
  • Expect to report clinical data from the VIVID trial (SC262 in B-cell malignancies) in 2025.

Challenges Ahead

  • No specific negative forward guidance was explicitly stated beyond the inherent risks of drug development and reliance on future funding.