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Dec 31, 2020

Sangamo Q4 2020 Earnings Report

Reported fourth quarter and full year 2020 financial results and recent business highlights.

Key Takeaways

Sangamo Therapeutics reported a consolidated net loss of $40.7 million for the fourth quarter ended December 31, 2020, compared to net income of $4.5 million for the same period in 2019. Revenues for the fourth quarter ended December 31, 2020 were $25.8 million, compared to $54.9 million for the same period in 2019. Cash, cash equivalents and marketable securities as of December 31, 2020 were $692.0 million, compared to $384.3 million as of December 31, 2019.

Presented updated follow-up data from the Phase 1/2 Alta study of giroctocogene fitelparvovec with Pfizer, demonstrating sustained Factor VIII activity levels.

Announced the first participant has been dosed in the registrational Phase 3 AFFINE trial of giroctocogene fitelparvovec with Pfizer.

Completed dosing of the third patient in the Phase 1/2 STAAR study evaluating ST-920 gene therapy for Fabry disease.

Brought in-house AAV manufacturing capabilities online in Sangamo’s Brisbane, California headquarters.

Total Revenue
$25.8M
Previous year: $54.9M
-53.0%
EPS
-$0.29
Previous year: $0.04
-825.0%
Gross Profit
-$26.6M
Previous year: $16.5M
-260.7%
Cash and Equivalents
$692M
Previous year: $385M
+79.7%
Free Cash Flow
-$8.31M
Previous year: -$27.6M
-69.9%
Total Assets
$939M
Previous year: $638M
+47.2%

Sangamo

Sangamo

Forward Guidance

On a GAAP basis, we expect total operating expenses in the range of approximately $285 million to $305 million in 2021, which includes non-cash stock-based compensation expense. We expect non-GAAP total operating expenses, excluding estimated non-cash stock-based compensation expense of approximately $30 million, in the range of approximately $255 million to $275 million.