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Mar 31, 2024

Syndax Q1 2024 Earnings Report

Syndax reported first quarter 2024 financial results and provided a business update.

Key Takeaways

Syndax Pharmaceuticals reported its financial results for the quarter ended March 31, 2024. The company highlighted the potential near-term approvals of revumenib and axatilimab, as well as pivotal data expected from the AUGMENT-101 trial in the fourth quarter. The company had cash, cash equivalents, and short and long-term investments of $522.0 million as of March 31, 2024.

NDA filing for revumenib in R/R KMT2Ar acute leukemia granted Priority Review under RTOR with a PDUFA action date set for September 26, 2024.

BLA filing for axatilimab in chronic GVHD granted Priority Review with a PDUFA action date set for August 28, 2024.

Enrollment completed in AUGMENT-101 mNPM1 cohort; topline data expected in 4Q24 to potentially support sNDA filing in 1H25.

Company to host conference call today at 8:00 a.m. ET.

Total Revenue
$0
EPS
-$0.85
Previous year: -$0.59
+44.1%
$56.5M
Previous year: $34.1M
+65.9%
$23M
Previous year: $12M
+92.5%
Total Operating Expenses
$79.5M
Previous year: $46M
+72.8%
Gross Profit
-$3K
Cash and Equivalents
$522M
Previous year: $449M
+16.3%
Free Cash Flow
-$83.5M
Total Assets
$543M
Previous year: $460M
+18.1%

Syndax

Syndax

Forward Guidance

For the second quarter of 2024, the Company expects research and development expenses to be $50 to $55 million and total operating expenses to be $80 to $85 million. For the full year of 2024, the Company continues to expect research and development expenses to be $240 to $260 million and total operating expenses to be $355 to $375 million, which includes an estimated $43 million in non-cash stock compensation expense. The Company believes that it has sufficient cash runway to fund its research, clinical development and commercial operations through 2026.