Dec 31, 2022

AcelRx Q4 2022 Earnings Report

Reported full year and fourth quarter 2022 financial results and provided a corporate update.

Key Takeaways

AcelRx Pharmaceuticals reported its Q4 2022 financial results, highlighting the divestment of DSUVIA to Alora Pharmaceuticals and progress in its Niyad™ nafamastat program. The company is focusing on late-stage assets and expects near-term corporate milestones by the end of Q2 2023, including an Emergency Use Authorization submission for Niyad and a New Drug Application for Fedsyra™.

AcelRx signed an agreement to divest DSUVIA to Alora Pharmaceuticals, expecting the transaction to close the week of April 3, 2023.

The company will receive a 15% royalty on commercial sales of DSUVIA and a 75% royalty on net sales to the Department of Defense.

AcelRx is advancing its Niyad™ nafamastat program with FDA Breakthrough designation, with accelerated stability testing supporting a planned Emergency Use Authorization submission in Q2 2023.

The company plans to submit an NDA for Fedsyra, its ephedrine pre-filled syringe (PFS) product candidate, by the end of next quarter.

Total Revenue
$252K
Previous year: $2K
+12500.0%
EPS
-$1
Previous year: -$1.2
-16.7%
Gross Profit
-$110K
Previous year: -$1.23M
-91.1%
Cash and Equivalents
$20.8M
Previous year: $51.6M
-59.7%
Free Cash Flow
-$5.46M
Previous year: -$8.03M
-32.0%
Total Assets
$47.5M
Previous year: $77.9M
-39.0%

AcelRx

AcelRx

Forward Guidance

AcelRx is focused on advancing its late-stage development pipeline, particularly the Niyad and Fedsyra programs. The company anticipates near-term milestones including regulatory submissions and clinical trial initiations.

Positive Outlook

  • Planned Emergency Use Authorization submission for Niyad in Q2 2023.
  • Initiation of the single registrational trial for Niyad expected in the second half of 2023.
  • NDA submission for Fedsyra by the end of next quarter.
  • Continued engagement and expansion of sales to the Department of Defense through the DSUVIA divestment agreement.
  • Market research confirms the urgent medical need for an alternative anticoagulant for use in continuous renal replacement therapy (CRRT).

Challenges Ahead

  • Risks relating to AcelRx's product development activities and ongoing commercial business operations
  • Risks related to the ability of AcelRx and its business partners to implement development plans, launch plans, forecasts and other business expectations
  • Risks related to unexpected variations in market growth and demand for AcelRx's commercial and developmental products and technologies
  • Risks related to AcelRx's liquidity and our ability to maintain capital resources
  • AcelRx's ability to retaining its listing on the Nasdaq exchange