Mar 31

UroGen Q1 2025 Earnings Report

UroGen reported a wider net loss in Q1 2025 despite revenue growth from JELMYTO, driven by increased R&D and SG&A expenses.

Key Takeaways

UroGen posted a net loss of $43.8 million in Q1 2025, with revenue increasing to $20.3 million due to continued demand for JELMYTO. However, higher operating costs tied to pipeline development and commercialization efforts weighed heavily on results.

JELMYTO revenue grew to $20.3 million, up from $18.8 million in Q1 2024.

Net loss expanded to $43.8 million primarily due to higher R&D and SG&A costs.

UGN-102’s FDA decision expected by June 13, 2025, with launch planned for July upon approval.

Cash and equivalents remained strong at $200.4 million, supporting ongoing pipeline development.

Total Revenue
$20.3M
Previous year: $18.8M
+7.8%
EPS
-$0.92
Previous year: -$0.97
-5.2%
R&D Expenses
$19.9M
Previous year: $15.5M
+28.2%
SG&A Expenses
$35M
Previous year: $27.3M
+28.1%
Gross Profit
$17.9M
Previous year: $17.1M
+5.1%
Cash and Equivalents
$200M
Previous year: $165M
+21.8%
Total Assets
$248M
Previous year: $201M
+23.5%

UroGen

UroGen

UroGen Revenue by Segment

Forward Guidance

UroGen reiterated its full-year 2025 guidance with expected JELMYTO revenue between $94M and $98M and operating expenses ranging from $215M to $225M.

Positive Outlook

  • Strong cash position supports near-term operations.
  • UGN-102 approval could unlock significant market opportunity.
  • Continued demand growth for JELMYTO.
  • Data supports durability and efficacy of UGN-102.
  • Enrollment progress in key clinical trials (e.g., UTOPIA for UGN-103).

Challenges Ahead

  • Rising operating costs leading to deeper net losses.
  • Dependence on timely FDA approval for UGN-102.
  • High SG&A due to commercialization readiness expenses.
  • Uncertainty around regulatory and advisory committee outcomes.
  • Increased interest and financing expenses from outstanding obligations.