Dec 31, 2024

UroGen Q4 2024 Earnings Report

UroGen reported solid Q4 2024 results, with JELMYTO revenue growing 5% year-over-year, while the company advanced its oncology pipeline.

Key Takeaways

UroGen's Q4 2024 revenue reached $24.6 million, reflecting a 5% year-over-year increase driven by higher JELMYTO demand. The company posted a net loss of $37.5 million due to increased R&D and SG&A expenses. JELMYTO continues to see growth in new patient starts and prescribers, and UroGen remains focused on advancing its UGN-102 NDA submission and pipeline assets.

JELMYTO revenue grew 5% year-over-year to $24.6 million.

Net loss widened to $37.5 million from $26.0 million in Q4 2023.

Operating expenses increased due to higher R&D and SG&A investments.

Cash and cash equivalents stood at $241.7 million as of December 31, 2024.

Total Revenue
$24.6M
Previous year: $23.5M
+4.4%
EPS
-$0.8
Previous year: -$0.72
+11.1%
R&D Expenses
$14.9M
Previous year: $11.3M
+31.8%
SG&A Expenses
$34.9M
Previous year: $24.6M
+42.0%
Gross Profit
$22.1M
Previous year: $21.2M
+4.0%
Cash and Equivalents
$242M
Previous year: $141M
+70.9%
Free Cash Flow
-$14M
Previous year: -$13.1M
+7.2%
Total Assets
$286M
Previous year: $178M
+60.2%

UroGen

UroGen

UroGen Revenue by Segment

Forward Guidance

UroGen expects continued revenue growth for JELMYTO in 2025 while focusing on the FDA review of UGN-102 and further advancing its pipeline.

Positive Outlook

  • 2025 JELMYTO revenue expected to grow 8-12% to $94-$98 million.
  • FDA PDUFA decision for UGN-102 expected by June 13, 2025.
  • Cash reserves remain strong at $241.7 million.
  • Continued growth in new prescribers and patient starts for JELMYTO.
  • Advancing clinical trials for next-generation urothelial cancer treatments.

Challenges Ahead

  • Net losses are expected to continue due to high R&D and SG&A costs.
  • Increased financing expenses related to the RTW Investments obligation.
  • Regulatory risks remain for the approval of UGN-102.
  • Competitive pressures in the urothelial cancer treatment market.
  • Uncertainty around macroeconomic factors affecting healthcare spending.