Dec 31, 2022

Lineage Q4 2022 Earnings Report

Reported financial and operating results for the fourth quarter and full year ended December 31, 2022.

Key Takeaways

Lineage Cell Therapeutics reported a net loss attributable to Lineage for the three months ended December 31, 2022 was $6.4 million, or $0.03 per share (basic and diluted). Total revenues for the three months ended December 31, 2022 were approximately $1.9 million.

Total revenues for Q4 2022 were $1.9 million, a net increase of $0.7 million compared to Q4 2021.

Operating expenses for Q4 2022 were $8.5 million, a decrease of $20.7 million compared to Q4 2021.

R&D expenses for Q4 2022 were $4.1 million, a decrease of $20.7 million compared to Q4 2021.

Net loss attributable to Lineage for Q4 2022 was $6.4 million, or $0.03 per share, compared to a net loss of $29.0 million, or $0.17 per share, for Q4 2021.

Total Revenue
$1.9M
Previous year: $1.2M
+58.3%
EPS
-$0.03
Previous year: -$0.17
-82.4%
Gross Profit
$1.81M
Previous year: $964K
+88.1%
Cash and Equivalents
$57.9M
Previous year: $55.7M
+3.9%
Free Cash Flow
-$8.29M
Previous year: -$6.03M
+37.4%
Total Assets
$124M
Previous year: $175M
-29.2%

Lineage

Lineage

Forward Guidance

Lineage anticipates several events and milestones in 2023, including publications, regulatory submissions, clinical trial initiations, and potential new partnerships.

Positive Outlook

  • Further progression of allogeneic cell therapy programs
  • Responsible investments in the expansion of novel approach to cell transplant medicine
  • Continued support of both newly established and existing collaborations
  • Potential for Phase 2a clinical study of OpRegen to be informative
  • Cash, cash equivalents and marketable securities expected to support planned operations into Q3 2024

Challenges Ahead

  • Need to allocate cash to unexpected events and expenses causing us to use our cash more quickly than expected
  • Positive findings in early clinical and/or nonclinical studies of a product candidate may not be predictive of success in subsequent clinical and/or nonclinical studies of that candidate
  • Competing alternative therapies may adversely impact the commercial potential of OpRegen
  • Roche and Genentech may not successfully advance OpRegen or be successful in completing further clinical trials for OpRegen and/or obtaining regulatory approval for OpRegen in any particular jurisdiction
  • Lineage may not be able to manufacture sufficient clinical quantities of its product candidates in accordance with current good manufacturing practice