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Dec 31, 2021

Pfizer Q4 2021 Earnings Report

Reported strong Q4 and full-year 2021 financial results, provided 2022 financial guidance, and raised Comirnaty revenue guidance while issuing Paxlovid revenue guidance.

Key Takeaways

Pfizer reported a strong fourth quarter with revenues of $23.8 billion, a 105% increase compared to the prior-year quarter. The company provided full-year 2022 revenue guidance of $98.0 to $102.0 billion and adjusted diluted EPS of $6.35 to $6.55. Pfizer also raised its Comirnaty revenue guidance to approximately $32 billion and issued initial Paxlovid revenue guidance of approximately $22 billion for 2022.

Q4 2021 revenues reached $23.8 billion, reflecting a 106% operational growth.

Reported diluted EPS for Q4 2021 was $0.59, while adjusted diluted EPS was $1.08.

Full-year 2021 revenues amounted to $81.3 billion, demonstrating a 92% operational growth.

Pfizer issued full-year 2022 revenue guidance of $98.0 to $102.0 billion and adjusted diluted EPS guidance of $6.35 to $6.55.

Total Revenue
$23.8B
Previous year: $11.7B
+104.0%
EPS
$1.08
Previous year: $0.42
+157.1%
SI&A Expenses
$4.1B
Previous year: $3.76B
+9.2%
R&D Expenses
$5.92B
Previous year: $3.35B
+76.4%
Effective Tax Rate
6.5%
Previous year: -95.9%
-106.8%
Gross Profit
$14.1B
Previous year: $8.77B
+60.9%
Cash and Equivalents
$1.94B
Previous year: $1.79B
+8.8%
Free Cash Flow
$4.92B
Previous year: $4.84B
+1.7%
Total Assets
$181B
Previous year: $154B
+17.7%

Pfizer

Pfizer

Pfizer Revenue by Segment

Pfizer Revenue by Geographic Location

Forward Guidance

Pfizer provided its 2022 financial guidance, including revenue expectations between $98.0 to $102.0 billion and adjusted diluted EPS of $6.35 to $6.55.

Positive Outlook

  • Midpoint of revenue guidance represents 23% growth from 2021 revenues.
  • Includes anticipated $32 billion of revenue for Comirnaty.
  • Includes anticipated $22 billion of revenue for Paxlovid.
  • Midpoint of adjusted diluted EPS guidance reflects a 46% increase over 2021 actual results.
  • Change in policy for intangible amortization expense is estimated to benefit adjusted diluted EPS by approximately $0.06.

Challenges Ahead

  • Assumes no completion of any business development transactions not completed as of December 31, 2021.
  • Reflects an anticipated negative revenue impact of $0.7 billion due to recent and expected generic and biosimilar competition.
  • Financial guidance reflects the anticipated unfavorable impact of approximately $1.1 billion on revenues and approximately $0.06 on Adjusted diluted EPS as a result of changes in foreign exchange rates.
  • Guidance for Adjusted diluted EPS assumes diluted weighted-average shares outstanding of approximately 5.8 billion shares, which assumes no share repurchases in 2022.
  • Expected increase in weighted average shares outstanding compared to 2021 of approximately 100 million shares has an unfavorable impact on 2022 Adjusted diluted EPS of $0.10.