Sep 30, 2024

Anaptysbio Q3 2024 Earnings Report

Anaptysbio's financial performance and business updates for Q3 2024 were reported.

Key Takeaways

AnaptysBio reported a net loss of $32.9 million for the third quarter of 2024, with collaboration revenue of $30.0 million. The company's cash and investments totaled $458.0 million, reiterating cash runway through year-end 2026. Clinical trial milestones for ANB032 and rosnilimab are anticipated in December 2024 and February 2025, respectively.

Top-line Phase 2b data for ANB032 in atopic dermatitis is anticipated in December 2024.

Top-line Phase 2b data for rosnilimab in rheumatoid arthritis is anticipated in February 2025.

Phase 1 trial initiated in healthy volunteers for ANB033.

Cash runway reiterated through year-end 2026, with cash and investments totaling $458.0 million as of September 30, 2024.

Total Revenue
$30M
Previous year: $3.32M
+804.7%
EPS
-$1.14
Previous year: -$1.41
-19.1%
Cash and Investments
$458M
Gross Profit
$29.4M
Previous year: $2.73M
+979.3%
Cash and Equivalents
$192M
Previous year: $413M
-53.6%
Free Cash Flow
-$10.1M
Previous year: -$36.2M
-72.0%
Total Assets
$493M
Previous year: $487M
+1.3%

Anaptysbio

Anaptysbio

Forward Guidance

AnaptysBio anticipates several clinical trial milestones and value drivers, including top-line data for ANB032 and rosnilimab, and the initiation of a Phase 1 trial for ANB033.

Positive Outlook

  • Top-line Phase 2b data for ANB032 in AD anticipated in December 2024
  • Top-line Phase 2b data for rosnilimab in RA anticipated in February 2025
  • Phase 1 trial initiated for ANB033 in healthy volunteers in October 2024
  • Plan to initiate enrollment for Phase 1 trial for ANB101 in healthy volunteers in Q1 2025
  • GSK anticipates top-line data in H1 2025 from COSTAR Lung Phase 3 trial

Challenges Ahead

  • The timing of the release of data from the Company’s clinical trials is uncertain.
  • The Company’s ability to find a licensing partner for imsidolimab or etokimab and the timing of any such transaction is uncertain.
  • The company’s projected cash runway is subject to change.
  • The potential to receive any additional royalties from the GSK collaboration is not guaranteed.
  • The company’s ability to advance its product candidates, obtain regulatory approval of and ultimately commercialize its product candidates is subject to risk.