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Dec 30, 2024
Carisma Therapeutics Q4 2024 Earnings Report
Carisma Therapeutics reported a net loss of $60.477 million and collaboration revenues of $19.632 million for Q4 2024.
Key Takeaways
Carisma Therapeutics experienced a net loss of $60.477 million in Q4 2024, an improvement from the $86.879 million loss in the prior year. Collaboration revenues increased to $19.632 million, driven by a development candidate nomination. The company implemented significant workforce reductions and ceased development of certain product candidates as part of its cash preservation plan, leading to decreased operating expenses.
Net loss improved to $60.477 million in 2024 from $86.879 million in 2023.
Collaboration revenues increased to $19.632 million in 2024 from $14.919 million in 2023, primarily due to a development candidate nomination.
Research and development expenses decreased by $14.452 million, reflecting a shift in strategic focus and workforce reductions.
The company implemented significant cost-reduction initiatives, including a 58% workforce reduction in 2024, and further reductions in March 2025 as part of a cash preservation plan.
Revenue by Segment
Forward Guidance
Carisma Therapeutics is currently focused on identifying and exploring strategic alternatives to maximize value and prepare for an orderly wind-down of operations, with no current intention of resuming research and development activities independently.
Positive Outlook
- The company is exploring a range of strategic alternatives, including sale, license, monetization, or divestiture of assets.
- The company aims to maximize the value of its assets, including CT-2401, CT-1119, and CAR-M platforms.
- Potential to realize value from milestone and royalty payments under the Moderna collaboration.
- The company has reduced operations to preserve existing cash resources.
- The company has retained employees deemed necessary to pursue strategic alternatives and execute an orderly wind down.
Challenges Ahead
- There is no assurance that the strategic review process will result in any type of transaction or realization of value for the company or stockholders.
- It is highly unlikely that there will be cash available for distribution to stockholders if a strategic alternative is not successfully identified or consummated.
Historical Earnings Impact
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Avg. Return Before/After Earnings
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