Cogent Biosciences reported a net loss of $11.3 million for the fourth quarter of 2020 and ended the quarter with $242.2 million in cash and cash equivalents.
CGT9486 clinical trial initiations are on track for Advanced Systemic Mastocytosis (1H21), Non-Advanced Systemic Mastocytosis (2H21), and Gastrointestinal Stromal Tumors (GIST) (2H21).
Final data from CGT9486 + sunitinib Phase 1/2 study demonstrated 12 months median PFS and 20% ORR in heavily pre-treated advanced GIST patients.
A randomized GIST clinical trial initiation is expected in 2H21.
The company ended Q4 2020 with $242.2 million in cash, funding operations into 2024.
Cogent Biosciences believes its cash and cash equivalents will be sufficient to fund operating expenses and capital expenditure requirements into 2024.